Don Wang

Education

2003-2010

1997-2002

Research Interests

My background is rooted in biotechnology, with a particular focus on harnessing the power of synthetic biology for therapeutic applications. Over the years, I've had the privilege of contributing to the development of cutting-edge therapeutic platforms for several pioneering cell therapy startups, where I witnessed firsthand the transformative potential of synthetic biology to improve human health. What truly excites me is the convergence of biotechnology and artificial intelligence, as I see immense potential in AI to tackle complex challenges in healthcare, from drug discovery to personalized medicine. This intersection of my professional accomplishments and interests has driven me to explore opportunities where I can continue to bridge the gap between biology and AI, ultimately making a positive impact on the future of healthcare.

Publications

Vejiga M, Wang DH, Li GG, Pratt K, Gip P, Trager, J, Chan I (2022) Immune Masking Strategies to Extend the Pharmacokinetics of Allogeneics Cell Therapies. AACR April 2022

DH, Lee HS, Yoon D, Berry G, Wheeler T, Sugarbaker D, Kheradmand F, Engelman E, Burt B. (2017)Progression of EGFR-mutant lung adenocarcinoma is driven by alveolar macrophage. Clinical Cancer Research.23(3):778-788 CY*, Wang DH*, Wang X, Dixon S, Meng L, Ahadi S, Enter D, Chen CY, Kato J, Leon L, Ramirez L, Maeda Y, Reis C, Ribeiro B, Weems B, Kung HJ, Lam KS. (2016) Rapid Discovery of Functional Small Molecule Ligands against Proteomic Targets through Library-Against-Library Screening. ACS Comb. Sci. 18(6):320-9 KV*, Wang DH* Campbell M, Huerta S, Shevchenko B, Izumiya C, Izumiya Y. (2014) PRMT4 Mediated Arginine Methylation Negatively Regulates Retinoblastoma Tumor Supressor Protein and Promotes E2F-1 Dissociation. MCB 35(1):238-248 M, Kim KY, Chang PC, Huerta S, Shevchenko B, Wang DH, Izumiya C, Kung HJ, Izumiya Y. (2013) A Lytic Viral Long Non-Coding RNA Modulates the Function of a Latent Protein. J. Virol.88(3):1843-8 Y, Kobayashi K, Kim KY, Pochampalli M, Izumiya C, Shevchenko B, Wang DH, Huerta S, Martinez A, Campbell M, Kung HJ. (2013) Kaposi’s sarcoma-associated herpesvirus K-Rta exhibits SUMO-targeting ubiquitin ligase (STUbL) activity which degrades SUMO and is essential for viral reactivation. PLoS Pathogen. 9(8):e1003506 KY, Huerta SB, Izumiya C, Wang DH, Martinez A, Shevchenko B, Kung HJ, Campbell M, Izumiya Y. (2013) Kaposi's sarcoma-associated herpesvirus (KSHV) latency- associated nuclear antigen regulates the KSHV epigenome by association with the histone demethylase KDM3A. J. Virol. 87(12):6782-93. M, Chang PC, Huerta S, Izumiya C, Davis R, Tepper CG, Kim KY, Shevchenko B, Wang DH, Jung JU, Luciw PA, Kung HJ, Izumiya Y. (2011) Protein Arginine Methyltransferase 1-directed Methylation of Kaposi Sarcoma-associated Herpesvirus Latency-associated Nuclear Antigen. J Biol Chem. 287(8):5806-18. PC, Fitzgerald LD, Van Geelen A, Izumiya Y, Ellison TJ, Wang DH, Ann DK, Luciw PA, Kung HJ. (2009) Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposi’s sarcoma-associated herpesvirus and its modulation by the viral protein kinase. Cancer Research.69(14):5681-9. Y, Izumiya C, Van Geelen A, Wang DH, Lam KS, Luciw PA, Kung HJ.(2007) Kaposi’s sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP. J Virol. 81(3):1072-82.