Lim Lab | Papers

The double life of PX domains

Kenneth E. Prehoda and Wendell A. Lim
Nature Structural Biology 8, 570-572 (2001)

Recent structural and cell biological studies show that the previously uncharacterized PX domain can bind both phospholipids and SH3 domains, suggesting that this module may play a critical role in coordinating membrane localization and protein complex assembly during cell signaling.