The Ste5 Scaffold Directs Mating Signaling by Catalytically Unlocking the Fus3 MAP Kinase for Activation
Matthew Good, Grace Tang, Julie Singleton, Attila Reményi, and Wendell A. Lim
Cell 136, 1085-97 (2009)

Structure	File
'Minimal scaffold' (ms) domain of Ste5	3FZE.pdb

The Ste5 Scaffold Allosterically Modulates Signaling Output of the Yeast Mating Pathway
Roby P. Bhattacharyya*, Attila Reményi*, Matthew C. Good, Caleb J. Bashor, Arnold M. Falick, and Wendell A. Lim
Science 311, 822-826 (2006)

Structure	File
Fus3 in complex with a Ste5 peptide	2F49.pdb
Fus3 without a peptide from Ste5	2FA2.pdb
Fus3 phosphorylated on Tyr182	2F9G.pdb

The role of docking interactions in mediating signaling input, output, and discrimination in the yeast MAPK network
Attila Reményi, Matthew C. Good, Roby P. Bhattacharyya, and Wendell A. Lim
Molecular Cell 20, 951-962 (2005)

Structure	File
Mitogen activated protein kinase Fus3 (non-phosphorylated)	2B9F.pdb
Fus3 with a docking motif from Ste7	2B9H.pdb
Fus3 with a docking motif from Msg5	2B9I.pdb
Fus3 with a docking motif from Far1	2B9J.pdb

Structure of the N-WASP EVH1 Domain-WIP Complex: Insight into the Molecular Basis of Wiskott-Aldrich Syndrome
Brian F. Volkman, Kenneth E. Prehoda, Jessica A. Scott, Francis C. Peterson, and Wendell A. Lim
Cell 111, 565–576 (2002)

Structure	File
N-WASP EVH1 Domain - WIP complex	1MKE.pdb

Structure of the SH3-Guanylate Kinase Module from PSD-95 Suggests a Mechanism for Regulated Assembly of MAGUK Scaffolding Proteins
Aaron W. McGee, Srikanth R. Dakoji, Olav Olsen, David S. Bredt, Wendell A. Lim, and Kenneth E. Prehoda
Molecular Cell 8, 1291-1301 (2001)

Structure	File
SH3-guanylate kinase module from PSD-95	1KJW.pdb

Structure of the Enabled/VASP Homology 1 Domain–Peptide Complex: A Key Component in the Spatial Control of Actin Assembly
Kenneth E. Prehoda, Do. J. Lee, and Wendell A. Lim
Cell 97, 471-480 (1999)

Structure	File
Enabled/VASP Homology 1 (EVH1) domain from mouse Enabled in complex with ActA peptide	1EVH.pdb

Unexpected Modes of PDZ Domain Scaffolding Revealed by Structure of nNOS-Syntrophin Complex
Brian J. Hillier, Karen S. Christopherson, Kenneth E. Prehoda, David S. Bredt, and Wendell A. Lim
Science 284, 812-815 (1999)

Structure	File
Neuronal nitric oxide synthase (nNOS) PDZ domain	1QAU.pdb
nNOS PDZ-syntrophin PDZ complex	1QAV.pdb

Exploiting the Basis of Proline Recognition by SH3 and WW Domains: Design of N-Substituted Inhibitors
Jack T. Nguyen, Christoph W. Turck, Fred E. Cohen, Ronald N. Zuckermann, and Wendell A. Lim
Science 282, 2088-2092 (1998)

Structure	File
Sem5 C-term. SH3 in complex with Sos peptide	1SEM.pdb
Sem5 C-term. SH3 in complex with isopropyl peptoid/peptide	2SEM.pdb
Sem5 C-term. SH3 in complex with cyclopropyl methyl peptoid/peptide	3SEM.pdb
Crk SH3 in complex with peptoid/peptide	1B07.pdb