Geoffrey | O'Donoghue


Postdoctoral Fellow


2014 - present

Postdoctoral Fellow
University of California, San Francisco

2008 - 2013
Ph.D. in Chemistry
University of California, Berkeley

2002 - 2006
B.A. in Chemistry
Williams College

Research Interests

Molecular organization and biophysics at cell:cell interfaces | T cell signaling | T cell therapeutics

Fellowships and Awards

2015 F32 Ruth L. Kirschstein National Reseaarch Service Award (NIH)
2010 Honorable Mention, Graduate Research Fellowship Program (NSF)
2006 Frank C. Goodrich Award for excellence in chemistry research (Williams College)
2005 Academic All-NESCAC Cross Country Team (Williams College)


Hartman, N.*; Kai, H.*; Liu, E.Y.*; Fay, N.; Yu, Y.; Lohmüller, T.; O'Donoghue, G.P.; Groves, J.T.; Size-based chromatography of signaling clusters in a living cell membrane. Nano Letters, in press. (* denotes equal authorship)

O'Donoghue, G.P.*; Pielak, R.M.*; Smoligovets, A.A.; Lin, J.J.; Groves, J.T.; Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells; eLife 2013;2:e00778 (* denotes equal authorship)

Lau, C.; Mirkovic, J.; Yu, C.C.; O'Donoghue, G.P.; et. al.; Early detection of high-grade squamous intraepithelial lesions in the cervix with quantitative spectroscopic imaging. J. Biomed. Opt. 2013; 18(7):76013

Belardi, B.; O'Donoghue, G.P.; Smith, A.W.; Groves, J.T.; Bertozzi, C.R.; Investigating Cell Surface Galectin-Mediated Cross-Linking on Glycoengineered Cells; J. Am. Chem. Soc. 2012,134, 9549-9552

Lohmüller, T.; Triffo, S.; O'Donoghue, G.P.; Xiu, Q.; Coyle, M.P.; Groves, J.T.; Supported Membranes Embedded with Fixed Arrays of Gold Nanoparticles; Nano Letters 11 (2011) 4912-4918

Yu, C.C.; Lau, C.; O'Donoghue, G.P.; Mirkovic, J.; McGee, S.; Galindo, L.; Elackattu, A.; Stier, E.; Grillone, G.; Badizadegan, K.; Dasari, R.R.; Feld, M.S.; Quantitative spectroscopic imaging for non-invasive early cancer detection; Optics Express 16 (2008) 16227-16239

Saar, B.G.; O'Donoghue, G.P.; Steeves, A.H.; Thoman, J.W.; Evidence for a blue-shifting intramolecular hydrogen bond in the vibrational overtone spectrum of 1Hnonafluorobutane; Chemical Physics Letters 417 (2006) 159-163