andrew    |    horwitz

ahorwitz cmp.ucsf.edu

Postdoctoral Fellow

Education

2006 - present
Postdoctoral Fellow
University of California, San Francisco

2001 - 2006
Ph.D., Experimental Pathology
Harvard Medical School

1995 - 1999
B.A., Biology
Pomona College

Fellowships and Awards

Jane Coffin Childs Memorial Fund for Medical Research Fellowship, July 2007 - present

Publications

Horwitz, A.A., Navon, A., Groll, M., Smith, D.M., Reis, C., and Goldberg, A.L. "ATP-induced structural transitions in PAN, the proteasome-regulatory ATPase complex in Archaea." Journal of Biological Chemistry 282, 22921-22929 (2007).

Horwitz, A.A., Affar, E.B., Heine, G.F., Shi, Y., and Parvin, J.D. "A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase." Proceedings of the National Academy of Sciences of the United States of America 1041, 6614-6619 (2007).

Horwitz, A.A., Sankaran, S., and Parvin, J.D. "Direct stimulation of transcription initiation by BRCA1 requires both its amino and carboxy-termini." Journal of Biological Chemistry 281, 8317-8320 (2006).

Simons, A.M., Horwitz, A.A., Starita, L.M., Griffin, K., Williams, R.S., Glover, J.N.M., and Parvin, J.D. "BRCA1 DNA binding activity is stimulated by BARD1." Cancer Research 66, 2012-2018 (2006).

Starita, L.M.*, Horwitz, A.A.*, Keogh, M.C., Ishioka, C., Parvin, J.D., and Chiba, N. "BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II." Journal of Biological Chemistry 280, 24498-24505 (2005). *Equal contribution.

Park, W.H., Margossian, S., Horwitz, A.A., Simons, A.M., D’Andrea, A.D., and Parvin, J.D. "Direct DNA binding of the Fanconi anemia D2 protein." Journal of Biological Chemistry 280, 23593-23598 (2005).